Feem ntau, cov poj niam mob ntawm kev mob ntawm mob taub hau, mob kev quav yeeb quav tshuaj , uas tsuas mob loj heev, thiab nws thiaj li tsis tuaj yeem pab. Triptans los ntawm migraine yog tiag tiag zoo - siv yeeb tshuaj tsim los mus kho tus kab mob no. Lawv tsis tsuas ceev qhov mob ntawm lub cev mob, tab sis tseem tiv thaiv kev mob, yog tias koj noj cov tshuaj nrog thawj cov tsos mob ntawm cov pathology.
Cov tshuaj ntawm cov neeg ua haujlwm pab pawg ua haujlwm li cas?
Lub ntsiab mechanism ntawm kev ua hauj lwm ntawm no hom ntawm cov tshuaj yog mus tsim kho lub receptors ntawm vascular phab ntsa. Tsis tas li ntawd, tryptans tsim cov kev xaiv zoo thiab ua rau tshwj xeeb tshaj yog nyob rau ntawm lub sijhawm qub, uas tsis cuam tshuam qhov kev mob plab hnyuv txhaws thiab peripheral. Yog li ntawd, cov hlab ntsha nqus cov hlab ntsha nqaim, uas muaj txiaj ntsim rau lub sijhawm txo ntawm qhov mob ntawm tus mob qhov mob.
Tsis tas li ntawd, cov lus piav qhia txo cov kev xav ntawm cov hlab ntsha qaum ntawm cov leeg ntawm cov leeg hlwb. Vim yog qhov mob no yuav luag tsis paub li.
Ntxiv nrog rau cov kev mob tshwm sim ntawm cov mob migraine , nrog rau xeev siab, lub teeb thiab suab nrov, kiv taub hau, tshuaj noj ntawm pawg neeg no yog siv los tiv thaiv cov hom phiaj. Lawv tau txo qhov kev ua kom tus mob neurogenic thiab tiv thaiv pulsation hauv cov hlab ntsha.
Triptans muaj ntau yam zoo dua li cov lus ceeb toom:
- ua rau muaj kev phiv ntau;
- Tsis txhob muaj kev quav yeeb quav tshuaj thiab qhov yuav tsum tau nce qis;
- ua haujlwm nyob rau txhua lub sij hawm ntawm kev sib cav;
- tiv thaiv qhov mob ntawm qhov mob, yog tias koj noj cov ntsiav tshuaj ntawm thawj cov tsos mob;
- txo cov cim qhia ntawm aura;
- tawm tsam nrog concomitant soj ntsuam tshwm ntawm tus kab mob.
Cov tshuaj twg muaj feem rau triptans?
Cov tshuaj nyob rau hauv nqe lus nug yog xim 5HT18 / D receptor antagonists. Lawv yog cov tshuaj derivatives ntawm 5-hydroxytryptamine, uas yuav tsum tau muaj npe.
Muaj ob tiam ntawm cov tshuaj muaj triptans. Thawj suav tag nrho cov tshuaj raws li sumatriptan - thawj tus neeg sawv cev ntawm cov pab pawg neeg. Qhov thib ob tiam muaj tshuaj nrog cov khoom xyaw nram qab no:
- zolmitriptan;
- eletriptan;
- naratriptan;
- almotriptan;
- rhizotriptan;
- lt; gt; & gt;
Cov tshuaj tshiab muaj ntau cov kab mob nyhuv dua thiab zoo dua qub. Lawv pab kom sai thiab ua rau muaj kev phiv tshuaj tsawg dua.
Nws yog tsim nyog sau cia tias kev siv qoob loo, rhizo- thiab fluorotriptans tseem muaj kev kuaj mob thiab tseem tab tom tshawb fawb, yog li lawv tseem tsis tau muaj kev pab dawb.
Sau cov tshuaj los ntawm migraine los ntawm cov pab pawg ntawm triptans
Yog xav tuaj tos kom nws tus kheej noj tshuaj rau nws mob taub hau nws zoo dua hauv qhov kev siv ntawm tus kws kho mob. Txawm tias tib txoj kev txiav txim siab ntawm cov neeg mus ncig tebchaws, txhua tus neeg mob tau txais kev pab los ntawm ib hom tshuaj, uas yuav pab xaiv ib tus kws paub tshwj xeeb tom qab kawm tau ceev faj txog tus yam ntxwv ntawm tus neeg mob thiab tus neeg mob.
Teev npe ntawm cov yeeb tshuaj:
1. Sumatriptans:
- Tshaj Tawm;
- Imigran;
- Sumatriptan;
- Trimigrene;
- Amigrenin;
- Sumygamren.
2. Zolmitriptans:
- Zomig.
3. Tus Neeg Hluas Taws Xob:
- Cov ntseeg.
4. Naratriptans:
- Naramig.
Kwv yees li ntawm ib nrab ntawm cov neeg muaj mob ntawm migraine tawm tsam muaj mob taub hau hauv 2 hnub txawm tias cov tshuaj tau piav qhia. Yog li ntawd, tsawg kawg 2 xuab moos tom qab noj cov tryptane, nws yog ib lub tswv yim kom noj lwm lub tshuaj ntawm cov tshuaj. Nws yog ib qho tseem ceeb uas tsis pub dhau ntau tshaj qhov pom zoo.