Glucocorticoid hormones yog ib qho tseem ceeb ntawm txoj kev kho mob hauv kev kho mob ntawm ntau cov kab mob nrog cov txheej txheem inflammatory. Xws li Dexamethasone - cov tshuaj los ntawm cov tshuaj no zoo heev thiab tib lub sij hawm muaj kev nyab xeeb. Nyob rau hauv kev sib piv nrog lwm cov kab mob glucocorticosteroids, tus neeg sawv cev no ua rau muaj kev phom sij ntau dua.
Pharmacological nta cov tshuaj ntawm Dexamethasone
Tus saib xyuas hormonal tsim tawm peb lub ntsiab teebmeem ntawm lub cev:
- anti-inflammatory;
- immunosuppressive;
- antiallergic.
Dexamethasone thiaj li ua rau lub cev ntawm cov kab mob qog nqaij hlav, uas yog tsim nyog rau kev kho mob ntawm ob sab hauv lub bronchi, thiab tseem txo qhov kev xiam oob qhab ntawm kev zais cia, ua kom nws qaug zog thaum hnoos.
Dexamethasone txhaj tshuaj dab tsi?
Ua ntej ntawm tag nrho cov, lub tshuaj nthuav tawm yog siv nyob rau hauv hormone hloov kho ntawm endocrine kab mob:
- Congenital hypoplasia ntawm lub qog nqaij;
- Addison tus kab mob;
- mob tsis ua hauj lwm ntawm adrenal cortex, ob qho tib si thawj thiab theem nrab;
- mob thiab thaij plab thawv;
- adrenogenital syndrome;
- qog nqaij hlav hypercalcemia;
- hypothyroidism.
Qhov qhia ntxiv rau kev siv cov tshuaj Dexamethasone los:
1. Tus mob Shocking:
- postoperative;
- tom qab kev puas ntsoog;
- tso ntshav mus ntxiv;
- cardiogenic;
- hlawv;
- lom.
2. Pathology ntawm txoj hlab ntsws:
- kev mob ntsws asthmatic;
- kis mob ua xua hnoos hawb pob;
- sarcoidosis ;
- exacerbation ntawm ntev obstructive bronchitis;
- hnyav bronchospasm;
- Leffler's disease;
- disseminated tuberculosis;
- berylliosis.
3. Kab mob ua npaws nrog:
- craniocerebral kev tuag;
- hemorrhages;
- qog;
- tus mob plab;
- cov kev ua neurosurgical;
- hluav taws xob raug mob ntawm lub ntsws;
- meningitis.
4. Cov kab mob Rheumatic:
- mob rheumatic plawv;
- rheumatoid kev mob caj dab thaum lub sijhawm exacerbation;
- disseminated lupus erythematosus.
5. Ntshav:
- idiopathic;
- autoimmune;
- congenital;
- erythroblastopenia;
- hemolytic;
- hypoplastic.
6. Kab mob ntawm lub plab system:
- kab mob siab;
- nephrotic syndrome;
- tsis muaj kab mob ntsws.
7. Hloov thiab muaj kev sib txuam ntawm cov pob qij txha thiab cov leeg:
- tenosynovitis;
- epicondylitis;
- mob caj dab;
- bursitis;
- osteochondrosis;
- styloidite;
- Bechterew tus kab mob;
- osteoarthritis;
- myositis.
8. Cov kab mob hauv cov ntshav:
- lwm yam kab mob thrombocytopenia;
- lymphomas;
- lymphocytic leukemia;
- idiopathic thrombocytopenic purpura;
- leukemia;
- plasmacytoma;
- agranulocytosis.
9. Ophthalmic pathologies:
- keratitis;
- Xirit;
- conjunctivitis;
- blepharitis;
- cov hlab ntaws (iridocyclitis) ;
- keratoconjunctivitis;
- sclerite;
- sympathetic ophthalmia;
- blepharoconjunctivitis;
- episcleritis;
- mob tom qab ua haujlwm ntawm lub qhov muag.
10. Daim tawv nqaij formations:
- liab ploj liab lupus erythematosus;
- keloids;
- annular granuloma;
- mob hnyav heev dermatosis.
Dexamethasone txhaj tshuaj kuj tseem hais txog kev ua xua, kev mob ntawm cov nqaij mob thiab cov mob hnyav. Nyob rau hauv rooj plaub tom kawg, tshuaj hormonal yog tas nrog cov tshuaj tua kab mob.
Yuav ua li cas kom hno Dexamethasone?
Cov mob hnyav thiab mob hnyav, cov tshuaj tua kab mob hauv cov tshuaj no yog muab tshuaj rau ntawm 4-20 mg (nyob ntawm txoj kev qhia txog kev mob) txog 4 zaug ib hnub. Qhov kev txhaj tshuaj yuav tsum tau ua kom qeeb qeeb, tsawg kawg yog 1 feeb.
Yog tias lub xeev kev noj qab haus huv zoo siab, cov tshuaj yuav tsum tau muab cov tshuaj tua kab mob zoo sib xws rau cov kab mob zoo sib xws.
Lub chav ntawm xws li kev kho yog 3-4 hnub, tswj ib koob tshuaj tom qab relieving exacerbation - 0.2-9 mg rau 24 teev. Yog tias yuav tsum tau kho ntxiv, mus rau Dexamethasone hauv daim ntawv ntawm cov ntsiav tshuaj.
Qee zaum cov tshuaj tua kab mob thiab cov khaub thuas hnyuv ntxig yog cov tshuaj. Nyob rau hauv xws li mob, lub txhua hnub koob tshuaj hormonal yog 0.2-6 mg.
Contraindications thiab kev phiv tshuaj los ntawm kev siv tshuaj Dexamethasone
Cov kab mob thiab tej yam kev mob uas cov ntsiab lus piav qhia tsis tuaj yeem siv:
- glaucoma;
- kis cov kab mob periarticular thiab pob qij txha;
- hypersensitivity;
- amoebic kab mob;
- active daim ntawv ntawm tuberculosis;
- tus kab mob me me;
- mob ntsws mob hlwb;
- sijhawm ua ntej thiab tom qab txhaj tshuaj tiv thaiv.
Xws li rau cov kev mob tshwm sim, Dexamethasone, raws li txoj cai, yog qhov ua tau zoo. Nyob rau qee zaum, muaj cov kab mob uas tsis yog xwm txheej ntawm cov hauv qab no:
- plab;
- plawv;
- endocrine;
- poob siab;
- musculoskeletal;
- tsis muaj zog.
Qee lub sij hawm ntawm daim tawv nqaij thiab cov kev xav hauv cheeb tsam raug pom, calcium metabolism, kev xav ntawm qee qhov kev xav hauv nruab nrog cev.