Sjogren's syndrome yog ib yam kab mob autoimmune uas ua rau kev puas tsuaj rau cov leeg khi. Los ntawm cov kab mob pathological, cov qog nqaij hlav - cov kua qaub thiab kua muag qog - raug kev txom nyem feem ntau ntawm tag nrho cov. Feem ntau, tus kab mob no yog ib qho kev kawm hnyav.
Sjogren's Syndrome - qhov mob yog dab tsi?
Ntawm lub complex ntawm cov tsos mob ntawm tus mob syndrome rau thawj lub sij hawm qhov saib xyuas tau them los ntawm Swedish kws kho mob kws kho mob Shegren tsawg dua ib puas xyoo dhau los. Nws pom ntau tus neeg mob uas tuaj rau nws nrog kev tsis txaus siab ntawm dryness nyob rau hauv ob lub qhov muag, ob peb lwm yam zoo tib yam cov tsos mob: ntev o ntawm pob qij txha thiab xerostomia - dryness ntawm lub qhov ncauj mucosa. Kev soj ntsuam xav tau lwm cov kws kho mob thiab cov kws tshawb fawb. Nws muab tawm tias cov kab mob pathology no tshwm sim thiab sib ntaus nws yuav tsum muaj kev kho mob.
Sjogren's syndrome - nws yog dab tsi? Tus kab mob autoimmune ntev no tuaj yeem tiv thaiv tsis tau tus keeb kwm ntawm kev tsis sib haum xeeb hauv lub cev. Tus kab mob no yuav siv nws lub hlwb rau cov kab txawv txawv teb chaws thiab pib mob cov tshuaj tiv thaiv rau lawv. Tawm tsam qhov tom qab no, txoj kev tsim teeb meem kev loj hlob tuaj, uas ua rau txo tus qog ntawm cov qog ntawm lwm cov kua qaub - feem ntau yog salivary thiab lacrimal.
Sjogren's Syndrome - Ua rau
Hais tsis meej tias yog vim li cas nws thiaj kho tus kab mob autoimmune, cov tshuaj kho tsis tau. Vim li no, qhov chaw qhuav qhuav ntawm Sjogren los ntawm qhov tsis paub. Nws paub tias genetic, immunological, hormonal thiab ib co sab nraud lwm yam koom rau hauv txoj kev loj hlob ntawm tus kab mob. Feem ntau, kab mob xws li cytomegalovirus, Epstein-Barr, herpes, los yog kab mob xws li polymyositis, systemic scleroderma, lupus erythematosus, rheumatoid mob caj dab ua lub zog ua rau txoj kev loj hlob ntawm tus kab mob.
Thawj Sjogren's Syndrome
Muaj ob hom mob loj. Tab sis lawv yog cov tib yam. Kev ziab ntawm cov qog hauv ob leeg raug tsim vim qog nqaij hlav qog ntawm cov qog ntawm cov qog nqaij hlav raws txoj hlab plawv thiab txoj hlab ntsws. Yog hais tias tus kab mob tshwm sim raws li ib qho kev ywj siab thiab tsis muaj dab tsi preceded nws tsos, ces qhov no yog thawj hom kab mob ntawm Sjogren.
Secondary Sjogren's Syndrome
Raws li kev xyaum qhia, qee zaum, tus kab mob no tshwm sim tawm tsam ntawm lwm cov kab mob. Raws li kev txheeb cais, ib qho mob qis me nyuam muaj nyob hauv 20 - 25% ntawm cov neeg mob. Nws muab tso rau thaum tus kab mob ua tau raws li cov teeb meem xws li mob rheumatoid mob caj dab, dermatomyositis, scleroderma thiab lwm yam kev txuam nrog qhov chaw ntawm cov nqaij mob.
Sjogren's syndrome - cov tsos mob
Tag nrho cov tshwm sim ntawm tus kab mob no yog muab faib ua glandular thiab ntxiv hlau. Qhov tseeb hais tias Sjogren's syndrome tau kis mus rau cov qog nqaij ntawm lub lacrimal yuav nkag siab los ntawm kev hnov mob ntawm kev kub ntxhov, "xuab zeb" nyob rau hauv ob lub qhov muag. Muaj ntau tus neeg tsis txaus siab ntawm qhov tawv ncauj khaus khaus. Feem ntau ob lub qhov muag tig liab, thiab nyob rau hauv cov ces kaum ntawm lawv accumulates ib tug dawb ntsws whitish tshuaj. Raws li tus kab mob vam meej, photophobia loj hlob, lub qhov muag ntxig pom tau tias yog nqaim, qhov muag pom tseeb deteriorates. Qhov nce hauv lacrimal qog yog ib qho tsis tshua muaj tshwm sim.
Yam ntxwv cwj pwm txawv ntawm Sjogren, uas cuam tshuam rau cov qog salivary: qhuav mucous nyob rau hauv lub qhov ncauj, liab ciam teb, di ncauj. Feem ntau, cov neeg mob tsim qhov qaug dab peg , thiab, ntxiv rau cov qog nqaij hlav, qee cov qog nyob ze. Thaum xub thawj, tus kab mob no nws ua rau nws tus kheej tsuas yog mob lub cev lossis lub siab lub ntsws. Tab sis tom qab lub dryness ua mus tas li, daim di ncauj yog them nrog crusts tias keej, uas ua rau kom muaj kev koom tes ntawm cov kab mob fungal.
Qee zaum, vim yog lub pob txha nyob rau hauv nasopharynx, cov crusts pib ua rau hauv lub qhov ntswg thiab lub tsho, uas tuaj yeem ua rau otitis thiab txawm qhov tsis hnov lus zoo. Thaum cov phevxim thiab lub suab caws qis heev dhau lawm, muaj qis thiab txhaws qa. Thiab nws kuj tau tshwm sim tias kev ua txhaum ntawm nqos tau ua rau atrophic gastritis. Tus kab mob yog tshwm sim los ntawm kev xeev siab, ua rau kev noj mov, hnyav hauv cheeb tsam epigastric tom qab noj mov.
Lub extragenital manifestations ntawm tus tsos mob ntawm Sjogren tus syndrome zoo li no:
- mob leeg;
- txoj leeg ntawm cov leeg thiab pob qij txha taub hau thaum sawv ntxov;
- leeg tsis muaj zog;
- cov pob khaus me ua pob uas tshwm sim tawm tsam tom qab ntawm cov leeg ntsha leeg;
- neuritis ntawm lub ntsej muag lossis lub ntsig txog ntshav qab zib;
- hemorrhagic pob ua pob liab liab thiab tawv nqaij;
- txhaws ntawm qhov chaw mos.
Sjogren's syndrome - sib txawv tshawb nrhiav
Lub ntsiab lus ntawm tus kab mob no yog los ntawm kev muaj cov kab mob hu ua xerophthalmia los yog xerostomia. Cov tom kawg yog tshawb tau los ntawm kev tshawb fawb los ntawm kev tshawb fawb, kev kuaj mob parotid scintigraphy thiab kev muag plab biopsy. Rau kev kuaj mob ntawm tus kab mob ntsws, tus Schirmer xeem tau ua tiav. Ib qho kawg ntawm ib kab xev ntawm cov ntawv lim yog tso rau hauv qab ntawm daim tawv muag sab laug thiab sab laug rau ib lub sij hawm. Nyob rau hauv cov neeg noj qab nyob zoo, tom qab li 5 feeb, txog li 15 hli ntawm kab txaij yuav ua ntub. Yog tias Sjogren's syndrome yog qhov tseeb, qhov kuaj pom tau tias nws tsis ntau tshaj 5 hli ntub.
Hauv kev ntsuam xyuas sib txawv nws yog qhov tseem ceeb uas yuav tsum nco ntsoov tias NLS tuaj yeem tsim muaj nrog rau cov kev kuaj mob xws li autoimmune thyroiditis, percinosis anemia, kab mob tshuaj. Lub ntsiab lus ntawm cov thawj lub cev qhuav yog zoo heev los ntawm kev tshawb nrhiav cov tshuaj tiv thaiv SS-B. Nws yog qhov nyuaj tshaj rau kev ntsuam xyuas Sjogren tus kab mob nrog mob rheumatoid, vim kev sib phom sib zog pib ntev ua ntej cov tsos mob ntawm cov tsos mob.
Sjogren's syndrome - kev tshuaj ntsuam
Kev kuaj ntawm tus kab mob no yuav ua kev sim cov kev kuaj sim. Thaum kuaj pom Sjogren tus kab mob, cov kev soj ntsuam qhia tau hais tias cov txiaj ntsig tau li nram qab no:
- Hauv kev ntsuas ntshav, kev ceev ESR, ntshav qab zib thiab qis ntshav dawb suav tau txiav txim siab.
- Tus OAM yog tus cwj pwm los ntawm muaj protein ntau.
- Cov protein kuj tau tsa rau hauv kev kuaj ntshav ntawm biochemical. Tsis tas li ntawd, txoj kev tshawb no qhia txog qhov siab tshaj plaws ntawm cov kab mob rheumatoid.
- Ib qho kev kuaj ntshav tshwj xeeb rau kev muaj cov tshuaj tiv thaiv rau thyroglobulin nyob rau hauv 35% qhia tau hais tias muaj kev nce hauv lawv cov concentration.
- Cov txiaj ntsim ntawm salivary caj pas biopsies lees paub cov tsos mob ntawm Sjogren's syndrome.
Sjögren's Syndrome - kev kho mob
Qhov no yog ib qho teeb meem loj, tab sis nws tsis yog neeg tuag taus. Yog hais tias koj xyuam xim rau nws cov cim hauv lub sij hawm thiab thaum koj kuaj mob Sjogren tus kab mob kev kho mob pib, koj tuaj yeem nyob nrog nws, koj xis nyob nrog nws. Qhov tseem ceeb tshaj plaws rau cov neeg mob yog tsis nco qab txog qhov tseem ceeb ntawm kev noj qab haus huv txoj kev ua neej. Qhov no yuav pab txhawb kev tiv thaiv tsis tau, yuav tsis pub tus kab mob pathological kom nquag txhim kho thiab txo cov kev pheej hmoo.
Nws puas tau los kho Sjogren's syndrome?
Thaum kuaj pom tseeb tias, tus neeg mob tau txais kev kho mob kom zoo. Sjogren's syndrome yog kho tau zoo hnub no, tab sis nws tseem tsis tau mus tua tus kab mob kiag li. Vim li no, tsuas yog kev kho cov tsos mob xwb. Cov kev ntsuas rau kev soj ntsuam cov kev kho mob yog qhov ua rau lub cev tshwm sim ntawm tus kab mob. Yog tias tag nrho cov hom phiaj kho mob, kev kuaj thiab duab keeb kwm zoo tuaj.
Sjögren's Syndrome - Kev Pom Zoo Cov Kws Kho Mob
Txoj kev kho mob ntawm lub cev qhuav no yuav ua rau cov kev mob tshwm sim tsis zoo thiab, yog tias tsim nyog, tiv thaiv kab mob keeb kwm yav dhau los. Ua ntej qhov kev kho mob ntawm Sjogren's syndrome, kev kuaj mob yog qhov ua tiav. Tom qab, raws li txoj cai, xws li tau siv:
- glucocorticoid Prednisolone (lub tswvyim thiab kev siv tshuaj yog txiav txim ib tus zuj zus raws li qhov hnyav ntawm qhov mob thiab qhov hnyav ntawm nws cov tsos mob);
- cov kws kho tshuab - Parmidin, Solcoseryl;
- immunomodulator Splenin;
- anticoagulant Heparin;
- Contrikal los yog Trasilol - yeeb tshuaj uas ua kom tsis muaj cov proteolytic enzymes;
- Zioostatics - Chlorbutin, Azathioprine, Cyclophosphamide (thawj pom zoo noj nrog glucocorticoids).
Txhawm rau tshem ntawm lub qhov ncauj qhuav, yaug. Lub qhov muag ntawm lub qhov muag qhuav yog kho nrog cov kua ntsev ntawm saline, Hemodesis. Qhuav bronchial leeg thiab trachea tuaj yeem kho nrog Bromhexine . Nrog rau ntawm qog Dimexide, Hydrocortisone los yog Heparin yog qhov muaj teeb meem. Qee lub qhov ncauj qhuav hauv kev kuaj mob ntawm Sjogren's syndrome ua rau kev loj hlob ntawm cov kab mob hniav. Yuav kom tiv thaiv tau lawv, koj yuav tsum tu xyuas qhov ncauj kom huv siab tshaj plaws.
Sjogren tus kab mob - kho nrog pej xeem tshuaj
Qhov mob hnyuv qhuav no yog ib qho ntawm cov tsos mob thiab cov cim. Nrog tag nrho nws yog qhov zoo dua los tua kev lig kev cai. Tab sis qee zaus nrog Sjogren's syndrome, pej xeem txoj kev siv rau hauv txoj kev pab tib neeg los txhim kho tus neeg mob. Qee cov neeg mob, piv txwv li, nco tias qhov muag tee ua los ntawm dill thiab qos kua txiv yog qhov zoo tshaj li cov tshuaj phais lacrimal kua.
Herbal decoction rau yaug
Cov khoom xyaw:
- chamomile paj - 1 tablespoon;
- SAGE nplooj - 1 tbsp. l.
- dej - 1 iav.
Kev npaj thiab siv:
- Grasses mix thiab maj mam grind.
- Dej boil thiab ncuav mus rau hauv ib qho qhuav sib tov.
- Cov tshuaj xav tau brew 40 feeb.
- Tom qab lim nws npaj txhij rau kev siv.
Sjogren's syndrome - kev pom zoo
Tus kab mob no tau ua rau tsis muaj kev hem thawj rau lub neej. Tab sis vim nws, qhov zoo ntawm lub neej ntawm cov neeg mob yog deteriorating noticeably. Kev kho yuav pab tiv thaiv kom tsis txhob muaj teeb meem thiab ua rau cov neeg laus ua haujlwm - Sjogren's syndrome hauv cov menyuam yaus yog qhov tsawg kawg. Yog hais tias kev kho tsis tau pib, tus kab mob no tuaj yeem tsim tau rau hauv daim ntawv loj, uas, thaum mob lwm yam kab mob, xws li bronchopneumonia , sinusitis los yog recurrent tracheitis, tej zaum kuj ua rau muaj mob xiam oob qhab.