HIV thiab AIDS yog cov kab mob uas tsis tsim kev mob, tab sis lawv txoj kev vam meej tuaj yeem txo qis qis qis qis ntawm cov tshuaj tshwj xeeb. Kev siv tshuaj antiretroviral nrog kev siv ntawm peb lossis plaub hom tshuaj nyob ntawm theem ntawm tus kab mob thiab cov tshuaj siv los ntawm tus kws kho mob.
Yuav kho tus mob antiretroviral li cas?
Tus kab mob immunodeficiency muaj siab mutagenicity. Qhov no txhais tau hais tias nws yog resistant rau ntau yam adverse teebmeem thiab yog hloov tau nws RNA, ua cov tshiab hloov mutations. Cov cuab yeej no tseem cuam tshuam cov kev kho mob ntawm HIV thiab AIDS, raws li cov kab mob pathogenic hloov sai heev rau cov tshuaj noj.
Kev siv tshuaj Antiretroviral yog ib qho ua ke ntawm 3-4 hom tshuaj kho mob, txhua yam uas muaj lub hauv paus ntsiab lus tshwj xeeb ntawm kev ua. Yog li, noj ntau hom tshuaj muaj kev tiv thaiv ntawm tsis yog lub ntsiab ntawm tus kab mob tseem ceeb xwb, tab sis kuj yog ib qho ntawm nws cov kev hloov ua thaum tsim txoj kev mob.
Thaum twg yog qhov kev kho mob antiretroviral?
Dua li, qhov kev kho mob HIV pib ua ntej pib, qhov zoo nws yuav ua kom qhov kev mob ntawm tus kab mob no, ua kom zoo thiab lub neej kev cia siab ntawm tus neeg mob. Vim tias cov tsos mob ntawm tus kab mob no feem ntau tsis paub tias, kev siv tshuaj antiretroviral yog li 5-6 xyoo tom qab kis tau tus kab mob, feem ntau lub sij hawm no nce mus txog 10 xyoo.
Cov tshuaj ntawm kev kho mob hnyav ua ke
Cov tshuaj muab faib rau cov chav kawm:
1. Inhibitors ntawm nrauv transcriptase (nucleoside):
- Yees duab;
- Tenofovir;
- Kivex;
- Retrovir;
- Abacavir;
- Zerit;
- Lamivudine;
- Trivizir;
- Emtriva.
2. Non-nucleoside thim rov qab transcriptase:
- Viramune;
- Stockrin;
- Delavirdine.
3. Protease inhibitors:
- Indinavir;
- Kaletra;
- Aptivus;
- Invisal;
- Ritonavir;
- Reyataz;
- Presista;
- Nelfinavir;
- Ageneraz;
- Telzir.
Inhibitors of fusion muaj rau chav kawm ntawv tshiab tshaj plaws ntawm kev siv tshuaj rau kev siv tshuaj antiretroviral. Li ntawd, tsuas yog ib qho tshuaj hu ua Fuzeon lossis Enfuvirtide.
Cov teebmeem tshwm sim ntawm kev siv tshuaj antiretroviral
Kev tsis zoo rau kev tsis zoo:
- cov tawv nqaij tawv;
- digestive mob;
- lipodystrophy;
- hyperlipidemia;
- tsis kam insulin;
- lipoatrophy;
- pathology ntawm lub hauv paus mob hlwb.
Cov teebmeem loj:
- raum pob zeb ;
- kev tsim txom ntawm pob txha pob txha;
- necrosis ntawm lub siab;
- lactic acidosis;
- Fanconi Syndrome;
- pancreatitis;
- hypersensitivity;
- Stevens-Johnson syndrome.